The Science Behind Folligen8®
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Meet the technology behind Folligen8® and explore the research featured in our formulation story. Here, we explain ROVISOME® Biotin, how the featured hair tonic study was carried out and what its findings can—and cannot—tell you.
Powered by ROVISOME® Biotin
Our Bioboosting Feed is formulated with 10% ROVISOME® Biotin, Evonik’s encapsulated ingredient system combining Biotin, Caffeine, Pro-Vitamin B5, Vitamin E and Lecithin.
The system is designed to support delivery of selected ingredients to the scalp and hair-root area. It brings delivery technology together with ingredients selected for a scalp-focused haircare routine.
What does 10% mean? It refers to the ROVISOME® ingredient system in the formulation, not 10% pure biotin.
The featured 24-week study
The study material below describes a leave-on hair tonic test formulation assessed in 12 participants: six men and six women with diffuse hair loss, aged 31–60.
- Application: once daily to the scalp for 24 weeks.
- Assessment points: after 6, 12, 18 and 24 weeks.
- Measurements: hair density and the ratio of growth-phase to resting-phase hair, using TrichoScan® analysis.
- User feedback: participant self-assessment, rated from very good to very poor.

Understanding the results
The study graphics below should be read alongside the methods and limitations. A small study of a test formulation is not a guarantee of an individual customer’s results.
Ingredient evidence and finished-product testing are different. The reproduced study excerpt does not identify the tested tonic as the exact finished retail Folligen8® serum. It should not be presented as proof that every Folligen8® product will achieve the same results.






Explore our plain-English explanation of the study science.
Your questions, answered
How long was the study?
The featured study ran for 24 weeks, with four assessment points. This is the study schedule, not a promise of when an individual customer will see a particular change.
Does the same evidence apply to shampoo and conditioner?
The study methods describe a leave-on tonic. They do not establish the same outcomes for rinse-off shampoo or conditioner.
What is the difference between in-vivo and ex-vivo research?
In-vivo research examines living subjects. Ex-vivo research examines tissue outside a living organism. These methods provide different kinds of evidence and should not be described interchangeably.
How should I use my products?
Follow the directions on your chosen product. The study routine described above should not replace its usage instructions.
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